Man’s Best Friend tells the tale of a dog and a girl who seem to be the perfect match for each other… They both love each other. The only problem is that her new Dog is a psychopathic animal that has been genetically altered to be a perfect killing machine!
Now the only way that her dog is being kept at bay is by a drug that was given to him by his originally owner, and if he doesn’t get another dose, her dog will revert back to being a killing machine, and kill everyone around him!